The dumb comments. I only got as far as saying my cancer is ER positive before a friend dove into a monologue about using estrogen cream on her ladybits due to a UTI, and then asking me if she was going to get cancer from it! Uhmmm, really? I thought we were talking about me. Then she just keeps on talking about herself, the excruciating details of her drama filled escapades. Always all about her......funny how I never noticed before dx.